The Double Non-Helix

By Ken Biegeleisen, M.D., Ph.D.

W-C helical structure in de-proteinized crystals.


DNA structure in living systems:  non-helical!

If you can patiently work your way through the PowerPoint presentations below, you will come to realize that the Watson-Crick double-helix structure is mainly an artifact of deproteinization and crystallization.


*Start Here*
Click here for 5-minute video introduction to non-helical DNA science.


(Not a scientist? Click *here* for our user-friendly Kickstarter video!)

If you intend to attempt the strand-separation
and/or reannealing experiments, click here.


View the PowerPoint slide presentations:





This presentation is based upon work done between 1972-2002. Slides 235-255, on the subject of "Form IV", have now been vastly superceded by the entire PowerPoint presentation on that subject (Form IV - the Final Puzzle Piece), which you will see lower down on this page.





This presentation was created in 2005. The section on histone structure (slides 12-30) has now been vastly superceded by the three PowerPoint presentations below, Histone Structure, Parts I-III.



















Published manuscripts:

Ken Biegeleisen, M.D., Ph.D.
New York, N.Y., USA
Tel: (212) 717-4422